{"id":6642,"date":"2019-10-03T08:10:15","date_gmt":"2019-10-03T07:10:15","guid":{"rendered":"https:\/\/icoprevencio.cat\/uct\/portfolio\/coste-efectividad-e-impacto-presupuestario-de-tres-estrategias-preventivas-en-cancer-de-pulmon\/"},"modified":"2022-03-07T14:33:49","modified_gmt":"2022-03-07T13:33:49","slug":"coste-efectividad-e-impacto-presupuestario-de-tres-estrategias-preventivas-en-cancer-de-pulmon","status":"publish","type":"portfolio","link":"https:\/\/icoprevencio.cat\/uct\/en\/portfolio\/coste-efectividad-e-impacto-presupuestario-de-tres-estrategias-preventivas-en-cancer-de-pulmon\/","title":{"rendered":"Cost-effectiveness and budgetary impact of three preventive strategies in lung cancer"},"content":{"rendered":"

Background<\/strong><\/span><\/p>\n

The prevalence of smoking in Spain is declining; however, both the incidence and mortality from lung cancer are increasing alarmingly among women and the trend is expected to continue to increase if no intervention is taken. In a general context of cost containment, health interventions should not only be evaluated in terms of health impact or in economic terms, but also in terms of efficiency.<\/p>\n

Objectives<\/strong><\/span><\/p>\n

    \n
  1. To define and estimate the Spanish population at high risk of developing lung cancer.<\/li>\n
  2. To determine the proportion of the population attended in Primary Health Care with a high risk of developing lung cancer.<\/li>\n
  3. To carry out an economic evaluation comparing the implementation of three preventive strategies in lung cancer with a no-intervention scenario, from the perspective of the National Health System (NHS) and from the social perspective. Cost-utility analysis is contemplated to measure health benefits as quality-adjusted life years, and cost-effectiveness analysis to measure health benefits as avoidable deaths from lung cancer.<\/li>\n
  4. To analyse the budgetary impact of the implementation of three preventive strategies in lung cancer in the NHS.<\/li>\n<\/ol>\n

    Methodology<\/strong><\/span><\/p>\n

    Objective 1: The data from the Spanish National Health Survey (ENSE) 2011-12 are used. The population at risk is described throughout the Spanish territory and stratified by sex and autonomous community.<\/p>\n

    Objective 2: The electronic medical record of Primary Health Care is explored. The assigned population and the population served at the Health Region of Barcelona are selected considering two age groups: 35-49 years (potentially at risk) and 50-75 years (high risk). The results are compared with the theoretical proportion obtained with the ENSE and confidence intervals of proportions are used to estimate statistically significant differences between both groups.<\/p>\n

    Objective 3: A hypothetical cohort with the characteristics of the adult population at high risk of developing lung cancer and the population potentially at risk is studied using the data from ENSE 2011-12. Primary and secondary prevention interventions applied to high-risk and potentially-at-risk population groups are combined: brief smoking cessation intervention, intensive smoking cessation intervention and organized screening. In order to determine the efficacy of each of the interventions, a systematic review of the literature is carried out to obtain different percentages of quitting smoking. The baseline scenario (no intervention) is compared with three preventive strategies, combining primary and secondary prevention interventions applied to both population groups.<\/p>\n

    Objective 4: The population at risk calculated from ENSE 2011-12 is considered. Two scenarios are estimated and compared, the current scenario and new hypothetical scenarios derived from the introduction of the different strategies, considering different percentages of implementation of such interventions.<\/p>\n

    Duration<\/strong><\/span><\/p>\n

    1 year, extended by 6 months (January 2017 to June 2018).<\/p>\n

    Funding<\/strong><\/span><\/p>\n

    Grants for cancer research projects, Spanish Association Against Cancer, AECC (\u20ac35,000).<\/p>\n

    Research team<\/strong><\/span><\/p>\n

    Ll\u00facia Benito (ICO-IDIBELL)<\/p>\n

    Gemma Binefa (ICO-IDIBELL)<\/p>\n

    Miseric\u00f2rdia Carles (URV)<\/p>\n

    Julieta Corral (ICO-IDIBELL)<\/p>\n

    Mireia D\u00edaz (ICO-IDIBELL)<\/p>\n

    Esteve Fern\u00e1ndez (ICO-IDIBELL)<\/p>\n

    Marcela Fu (IP, ICO-IDIBELL)<\/p>\n

    Montse Garc\u00eda (IP, ICO-IDIBELL)<\/p>\n

    Carlos Mart\u00edn (CAP Passeig de Sant Joan)<\/p>\n

    Amparo Romaguera (ICO)<\/p>\n

    Albert Santiago (ICO-IDIBELL)<\/p>\n

    Carmen Vidal (ICO-IDIBELL)<\/p>\n

    Montserrat Ru\u00e9 (IRB Lleida)<\/p>\n

    Marta Trapero-Bertran (UIC)<\/p>\n

    Results<\/strong><\/span><\/p>\n

    1: Fu M, Travier N, Mart\u00edn-S\u00e1nchez JC, Mart\u00ednez-S\u00e1nchez JM, Vidal C, Garcia M; LUCAPREV research group. Identifying high-risk individuals for lung cancer\u00a0<\/span>screening: Going beyond NLST criteria. PLoS One. 2018;13(4):e0195441. doi:\u00a010.1371\/journal.pone.0195441<\/a>. PMID:\u00a029621354<\/a>; PMCID:\u00a0PMC5886563<\/a>.<\/span><\/p>\n

    \u00a0<\/span><\/p>\n

    2: Travier N, Fu M, Romaguera A, Mart\u00edn-Cantera C, Fern\u00e1ndez E, Vidal C, Garcia M; LUCAPREV research group. 6-Year Risk of Developing Lung Cancer in Spain:\u00a0<\/span>Analysis by Autonomous Communities. Arch Bronconeumol. 2021;57(8):521-7. doi:\u00a010.1016\/j.arbres.2020.03.022<\/a>. PMID:\u00a032402549<\/a>.<\/span><\/p>\n

    \u00a0<\/span><\/p>\n

    3: Diaz M, Garcia M, Vidal C, Santiago A, Gnutti G, G\u00f3mez D, Trapero-Bertran M, Fu M; Lung Cancer Prevention LUCAPREV research group. Health and economic impact at a population level of both primary and secondary preventive lung cancer interventions: A model-based cost-effectiveness analysis. Lung Cancer. 2021;159:153-161. doi:\u00a010.1016\/j.lungcan.2021.06.027<\/a>. PMID:\u00a034352591<\/a>.<\/span><\/p>\n

    Podcast Travier:<\/strong><\/p>\n

    https:\/\/multimedia.elsevier.es\/PublicationsMultimediaV1\/item\/multimedia\/stream\/S0300289620301034:mmc1.mp3?idApp=UINPBA00003Z<\/a><\/p>\n

    Communications to congresses<\/strong><\/span><\/p>\n

    Comunication poster: Santiago A, Fu M, Vidal C, Trapero M, Garcia M, D\u00edaz M. Model de simulaci\u00f3 matem\u00e0tica per avaluar estrat\u00e8gies de prevenci\u00f3 de c\u00e0ncer de pulm\u00f3. Jornada I+D MESIO UPC-UB, 9 mayo 2018.<\/p>\n

    Oral comunication: Santiago-Bo\u00edl A, Fu M, Vidal C, Garcia M, D\u00edaz M. Cost-effectiveness analysis of lung cancer prevention strategies. XXXVIII Jornadas de Econom\u00eda de la Salud; Las Palmas de Gran Canaria, 20-22 junio 2018.<\/p>\n

    Oral comunication: Santiago-Bo\u00edl A, Fu M, Vidal C, Garcia M, D\u00edaz M. Cost-effectiveness analyses of lung cancer prevention strategies. XXIX International Biometric Conference; Barcelona, 8-13 julio 2018.<\/p>\n

    Oral comunication: Vidal C, Fu M, Travier N, Garc\u00eda M. Estratificaci\u00f3n del riesgo de c\u00e1ncer de pulm\u00f3n en la poblaci\u00f3n espa\u00f1ola. Implicaciones para la prevenci\u00f3n. XXXVI Reuni\u00f3n Anual de la Sociedad Espa\u00f1ola de Epidemiolog\u00eda (SEE) y XIII Congresso da Associa\u00e7\u00e3o Portuguesa de Epidemiologia (APE), Lisboa, 11-14 setiembre 2018.<\/p>\n

    Comunication poster: Garcia M, Fu M, Travier N, Vidal C. Identifying high-risk individuals for lung cancer screening\u2013going beyond NELSON and NLST eligibility criteria. International Cancer Screening Network Conference, Rotterdam, 3-5 junio 2019.<\/p>\n

    Oral comunication: Garcia M, Vidal C, Santiago A, Fu M, Rue M, Carles-Lavila M, Trapero-Bertran M, D\u00edaz M, Lung Cancer Prevention research group. A cost-effectiveness analysis of lung cancer prevention strategies at population level combining smoking cessation interventions and early detection with low-dose computed tomography in Spain. International Cancer Screening Conference, Rotterdam, 3-5 junio 2019.<\/p>\n

    D\u00edaz M, Garc\u00eda M, Vidal C, Santiago A, Rue M, Carles-Lavila M, Trapero-Bertran M, Fu M, Grupo de trabajo LUCAPREV. An\u00e1lisis de coste-efectividad de estrategias preventivas de c\u00e1ncer de pulm\u00f3n en Espa\u00f1a. XXXVII Reuni\u00f3n Anual de la Sociedad Espa\u00f1ola de Epidemiolog\u00eda (SEE), XIV Congresso da Associa\u00e7\u00e3o Portuguesa de Epidemiologia (APE) y XVIII Congreso de la Sociedad Espa\u00f1ola de Sociedad Espa\u00f1ola de Salud P\u00fablica y Administraci\u00f3n Sanitaria (SESPAS), Oviedo, 3-6 setiembre 2019.<\/p>\n

    Master’s Thesis<\/strong><\/span><\/p>\n

    Title: Lung Cancer Model for Evaluating Cancer Control Interventions.<\/p>\n

    Student: Albert Santiago Bo\u00edl.<\/p>\n

    Director: Mireia D\u00edaz Sanchis.<\/p>\n

    Co-Director: Klaus Gerhard Langohr.<\/p>\n

    Program: Master of Science in Advanced Mathematics and Mathematical Engineering<\/p>\n

    Center: Departamento de Estad\u00edstica e Investigaci\u00f3n Operativa, UPC<\/p>\n

    Defense date: 16 mayo 2018.<\/p>\n","protected":false},"excerpt":{"rendered":"

    Background The prevalence of smoking in Spain is declining; however, both the incidence and mortality from lung cancer are increasing alarmingly among women and the trend is expected to continue to increase if no intervention is taken. In a general context of cost containment, health interventions should not only be evaluated in terms of health 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In a general context of cost containment, health interventions should not only be evaluated in terms of health…","_links":{"self":[{"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/portfolio\/6642","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/portfolio"}],"about":[{"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/types\/portfolio"}],"author":[{"embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/comments?post=6642"}],"version-history":[{"count":1,"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/portfolio\/6642\/revisions"}],"predecessor-version":[{"id":8110,"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/portfolio\/6642\/revisions\/8110"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/media\/6640"}],"wp:attachment":[{"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/media?parent=6642"}],"wp:term":[{"taxonomy":"portfolio_category","embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/portfolio_category?post=6642"},{"taxonomy":"portfolio_tag","embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/en\/wp-json\/wp\/v2\/portfolio_tag?post=6642"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}