{"id":6641,"date":"2019-10-03T08:10:15","date_gmt":"2019-10-03T07:10:15","guid":{"rendered":"https:\/\/icoprevencio.cat\/uct\/portfolio\/coste-efectividad-e-impacto-presupuestario-de-tres-estrategias-preventivas-en-cancer-de-pulmon\/"},"modified":"2024-06-05T09:48:29","modified_gmt":"2024-06-05T08:48:29","slug":"coste-efectividad-e-impacto-presupuestario-de-tres-estrategias-preventivas-en-cancer-de-pulmon","status":"publish","type":"portfolio","link":"https:\/\/icoprevencio.cat\/uct\/portfolio\/coste-efectividad-e-impacto-presupuestario-de-tres-estrategias-preventivas-en-cancer-de-pulmon\/","title":{"rendered":"Cost-efectivitat i impacte pressupostari de tres estrat\u00e8gies preventives en c\u00e0ncer de pulm\u00f3"},"content":{"rendered":"

Antecedents<\/strong><\/span><\/p>\n

La prevalen\u00e7a de tabaquisme a Espanya est\u00e0 disminuint; malgrat aix\u00f2, tant la incid\u00e8ncia com la mortalitat per c\u00e0ncer de pulm\u00f3 estan augmentant de manera alarmant entre les dones i es preveu que la tend\u00e8ncia continu\u00ef en augment si no s’interv\u00e9. En un context general de contenci\u00f3 de la despesa, les intervencions sanit\u00e0ries no nom\u00e9s han de ser avaluades en termes d’impacte en salut o en termes econ\u00f2mics, sin\u00f3 tamb\u00e9 en termes d’efici\u00e8ncia.<\/p>\n

Objectius<\/strong><\/span><\/p>\n

    \n
  1. Definir i estimar la poblaci\u00f3 espanyola amb un alt risc de desenvolupar un c\u00e0ncer de pulm\u00f3.<\/li>\n
  2. Determinar la proporci\u00f3 de poblaci\u00f3 atesa en Atenci\u00f3 Prim\u00e0ria amb un alt risc de desenvolupar c\u00e0ncer de pulm\u00f3.<\/li>\n
  3. Realitzar una avaluaci\u00f3 econ\u00f2mica comparant la implementaci\u00f3 de tres estrat\u00e8gies preventives en c\u00e0ncer de pulm\u00f3 amb un escenari de no intervenci\u00f3, des de la perspectiva del Sistema Nacional de Salut (SNS) i des de la perspectiva social. Es contempla una an\u00e0lisi de cost-utilitat per mesurar el benefici en salut com anys de vida guanyats ajustats per qualitat de vida, i una an\u00e0lisi de cost-efectivitat per mesurar el benefici en salut com morts evitables per c\u00e0ncer de pulm\u00f3.<\/li>\n
  4. Analitzar l’impacte pressupostari de la implementaci\u00f3 de tres estrat\u00e8gies preventives en c\u00e0ncer de pulm\u00f3 en el SNS.<\/li>\n<\/ol>\n

    Metodologia<\/strong><\/span><\/p>\n

    Objectiu 1: S’utilitzen les dades de l’Enquesta Nacional de Salut d’Espanya (ENSE) 2011-12. Es descriu la poblaci\u00f3 a risc en tot el territori espanyol i estratificat per sexe i per comunitat aut\u00f2noma.<\/p>\n

    Objectiu 2: S’explora la hist\u00f2ria cl\u00ednica electr\u00f2nica d’Atenci\u00f3 Prim\u00e0ria. Se selecciona la poblaci\u00f3 assignada i la poblaci\u00f3 atesa a la Regi\u00f3 Sanit\u00e0ria de Barcelona considerant dos grups d’edat: 35-49 anys (potencialment a risc) i 50-75 anys (alt risc). Es comparen els resultats amb la proporci\u00f3 te\u00f2rica obtinguda amb l’ENSE i es calculen intervals de confian\u00e7a de proporcions per estimar difer\u00e8ncies estad\u00edsticament significatives entre ambd\u00f3s grups.<\/p>\n

    Objectiu 3: S’estudia una cohort hipot\u00e8tica amb les caracter\u00edstiques de la poblaci\u00f3 adulta amb alt risc de desenvolupar un c\u00e0ncer de pulm\u00f3 i de la poblaci\u00f3 potencialment a risc utilitzant les dades de l’ENSE 2011-12. Es combinen intervencions de prevenci\u00f3 prim\u00e0ria i secund\u00e0ria aplicades a grups de poblaci\u00f3 d’alt risc i potencialment a risc: intervenci\u00f3 breu per deixar de fumar, tractament intensiu per deixar de fumar i cribratge organitzat. Per determinar l’efic\u00e0cia de cadascuna de les intervencions es realitza una revisi\u00f3 sistem\u00e0tica de la literatura per obtenir diferents percentatges d’abandonament del consum. Es compara l’escenari basal (no intervenci\u00f3) amb tres estrat\u00e8gies preventives, que combinen intervencions de prevenci\u00f3 prim\u00e0ria i secund\u00e0ria aplicades a ambd\u00f3s grups de poblaci\u00f3.<\/p>\n

    Objectiu 4: Es considera la poblaci\u00f3 a risc calculada a partir de l\u2019ENSE 2011-12. S’estimen i comparen dos escenaris, l’escenari actual i nous escenaris hipot\u00e8tics derivats de la introducci\u00f3 de les diferents estrat\u00e8gies, contemplant diferents percentatges d’implementaci\u00f3 de les intervencions.<\/p>\n

    Durada<\/strong><\/span><\/p>\n

    1 any, prorrogat 6 mesos (gener 2017 a juny 2018).<\/p>\n

    Finan\u00e7ament<\/strong><\/span><\/p>\n

    Ajuts per a projectes de recerca en c\u00e0ncer, Associaci\u00f3 Espanyola Contra el C\u00e0ncer (35.000 \u20ac).<\/p>\n

    Equip investigador<\/strong><\/span><\/p>\n

    Ll\u00facia Benito (ICO-IDIBELL)<\/p>\n

    Gemma Binefa (ICO-IDIBELL)<\/p>\n

    Miseric\u00f2rdia Carles (URV)<\/p>\n

    Julieta Corral (ICO-IDIBELL)<\/p>\n

    Mireia D\u00edaz (ICO-IDIBELL)<\/p>\n

    Esteve Fern\u00e1ndez (ICO-IDIBELL)<\/p>\n

    Marcela Fu (IP, ICO-IDIBELL)<\/p>\n

    Montse Garc\u00eda (IP, ICO-IDIBELL)<\/p>\n

    Carlos Mart\u00edn (CAP Passeig de Sant Joan)<\/p>\n

    Amparo Romaguera (ICO)<\/p>\n

    Albert Santiago (ICO-IDIBELL)<\/p>\n

    Carmen Vidal (ICO-IDIBELL)<\/p>\n

    Montserrat Ru\u00e9 (IRB Lleida)<\/p>\n

    Marta Trapero-Bertran (UIC)<\/p>\n

    Resultats<\/strong><\/span><\/p>\n

    1: Fu M, Travier N, Mart\u00edn-S\u00e1nchez JC, Mart\u00ednez-S\u00e1nchez JM, Vidal C, Garcia M; LUCAPREV research group. Identifying high-risk individuals for lung cancer <\/span>screening: Going beyond NLST criteria. PLoS One. 2018;13(4):e0195441. doi: 10.1371\/journal.pone.0195441<\/a>. PMID: 29621354<\/a>; PMCID: PMC5886563<\/a>.<\/span><\/p>\n

    \u00a0<\/span><\/p>\n

    2: Travier N, Fu M, Romaguera A, Mart\u00edn-Cantera C, Fern\u00e1ndez E, Vidal C, Garcia M; LUCAPREV research group. 6-Year Risk of Developing Lung Cancer in Spain: <\/span>Analysis by Autonomous Communities. Arch Bronconeumol. 2021;57(8):521-7. doi: 10.1016\/j.arbres.2020.03.022<\/a>. PMID: 32402549<\/a>.<\/span><\/p>\n

    \u00a0<\/span><\/p>\n

    3: Diaz M, Garcia M, Vidal C, Santiago A, Gnutti G, G\u00f3mez D, Trapero-Bertran M, Fu M; Lung Cancer Prevention LUCAPREV research group. Health and economic impact at a population level of both primary and secondary preventive lung cancer interventions: A model-based cost-effectiveness analysis. Lung Cancer. 2021;159:153-161. doi: 10.1016\/j.lungcan.2021.06.027<\/a>. PMID: 34352591<\/a>.<\/span><\/p>\n

    Podcast publicaci\u00f3 Travier: https:\/\/multimedia.elsevier.es\/PublicationsMultimediaV1\/item\/multimedia\/stream\/S0300289620301034:mmc1.mp3?idApp=UINPBA00003Z<\/a><\/p>\n

    Comunicacions a congressos<\/strong><\/span><\/p>\n

    Comunicaci\u00f3 p\u00f2ster: Santiago A, Fu M, Vidal C, Trapero M, Garcia M, D\u00edaz M. Model de simulaci\u00f3 matem\u00e0tica per avaluar estrat\u00e8gies de prevenci\u00f3 de c\u00e0ncer de pulm\u00f3. Jornada I+D MESIO UPC-UB, 9 maig 2018.<\/p>\n

    Comunicaci\u00f3 oral: Santiago-Bo\u00edl A, Fu M, Vidal C, Garcia M, D\u00edaz M. Cost-effectiveness analysis of lung cancer prevention strategies. XXXVIII Jornadas de Econom\u00eda de la Salud; Las Palmas de Gran Canaria, 20-22 juny 2018.<\/p>\n

    Comunicaci\u00f3 oral: Santiago-Bo\u00edl A, Fu M, Vidal C, Garcia M, D\u00edaz M. Cost-effectiveness analyses of lung cancer prevention strategies. XXIX International Biometric Conference; Barcelona, 8-13 juliol 2018.<\/p>\n

    Comunicaci\u00f3 oral: Vidal C, Fu M, Travier N, Garc\u00eda M. Estratificaci\u00f3n del riesgo de c\u00e1ncer de pulm\u00f3n en la poblaci\u00f3n espa\u00f1ola. Implicaciones para la prevenci\u00f3n. XXXVI Reuni\u00f3n Anual de la Sociedad Espa\u00f1ola de Epidemiolog\u00eda (SEE) y XIII Congresso da Associa\u00e7\u00e3o Portuguesa de Epidemiologia (APE), Lisboa, 11-14 setembre 2018.<\/p>\n

    Comunicaci\u00f3 poster Garcia M, Fu M, Travier N, Vidal C. Identifying high-risk individuals for lung cancer screening\u2013going beyond NELSON and NLST eligibility criteria. International Cancer Screening Network Conference, Rotterdam, 3-5 juny 2019.<\/p>\n

    Comunicaci\u00f3 oral: Garcia M, Vidal C, Santiago A, Fu M, Rue M, Carles-Lavila M, Trapero-Bertran M, D\u00edaz M, Lung Cancer Prevention research group. A cost-effectiveness analysis of lung cancer prevention strategies at population level combining smoking cessation interventions and early detection with low-dose computed tomography in Spain. International Cancer Screening Conference, Rotterdam, 3-5 juny 2019.<\/p>\n

    D\u00edaz M, Garc\u00eda M, Vidal C, Santiago A, Rue M, Carles-Lavila M, Trapero-Bertran M, Fu M, Grupo de trabajo LUCAPREV. An\u00e1lisis de coste-efectividad de estrategias preventivas de c\u00e1ncer de pulm\u00f3n en Espa\u00f1a. XXXVII Reuni\u00f3n Anual de la Sociedad Espa\u00f1ola de Epidemiolog\u00eda (SEE), XIV Congresso da Associa\u00e7\u00e3o Portuguesa de Epidemiologia (APE) y XVIII Congreso de la Sociedad Espa\u00f1ola de Sociedad Espa\u00f1ola de Salud P\u00fablica y Administraci\u00f3n Sanitaria (SESPAS), Oviedo, 3-6 setembre 2019.<\/p>\n

    Treball de Fi de M\u00e0ster<\/strong><\/span><\/p>\n

    T\u00edtol: Lung Cancer Model for Evaluating Cancer Control Interventions.<\/p>\n

    Alumne: Albert Santiago Bo\u00edl.<\/p>\n

    Directora: Mireia D\u00edaz Sanchis.<\/p>\n

    Co-Director: Klaus Gerhard Langohr.<\/p>\n

    Programa: Master of Science in Advanced Mathematics and Mathematical Engineering<\/p>\n

    Centre: Departamento de Estad\u00edstica e Investigaci\u00f3n Operativa, UPC<\/p>\n

    Data de defensa: 16 maig 2018.<\/p>\n","protected":false},"excerpt":{"rendered":"

    Antecedents La prevalen\u00e7a de tabaquisme a Espanya est\u00e0 disminuint; malgrat aix\u00f2, tant la incid\u00e8ncia com la mortalitat per c\u00e0ncer de pulm\u00f3 estan augmentant de manera alarmant entre les dones i es preveu que la tend\u00e8ncia continu\u00ef en augment si no s’interv\u00e9. En un context general de contenci\u00f3 de la despesa, les intervencions sanit\u00e0ries no nom\u00e9s […]<\/p>\n","protected":false},"author":15,"featured_media":6639,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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La prevalen\u00e7a de tabaquisme a Espanya est\u00e0 disminuint; malgrat aix\u00f2, tant la incid\u00e8ncia com la mortalitat per c\u00e0ncer de pulm\u00f3 estan augmentant de manera alarmant entre les dones i es preveu que la tend\u00e8ncia continu\u00ef en augment si no s’interv\u00e9. En un context general de contenci\u00f3 de la despesa, les intervencions sanit\u00e0ries no nom\u00e9s…","_links":{"self":[{"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/portfolio\/6641","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/portfolio"}],"about":[{"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/types\/portfolio"}],"author":[{"embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/comments?post=6641"}],"version-history":[{"count":3,"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/portfolio\/6641\/revisions"}],"predecessor-version":[{"id":9888,"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/portfolio\/6641\/revisions\/9888"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/media\/6639"}],"wp:attachment":[{"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/media?parent=6641"}],"wp:term":[{"taxonomy":"portfolio_category","embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/portfolio_category?post=6641"},{"taxonomy":"portfolio_tag","embeddable":true,"href":"https:\/\/icoprevencio.cat\/uct\/wp-json\/wp\/v2\/portfolio_tag?post=6641"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}